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. 1988 Jan;29(1):239-46.
doi: 10.1002/ajmg.1320290138.

Localization of the gene for X-linked nephrogenic diabetes insipidus to Xq28

M Kambouris  1 , S R Dlouhy, J A Trofatter, P M Conneally, M E Hodes
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Localization of the gene for X-linked nephrogenic diabetes insipidus to Xq28

M Kambouris et al. Am J Med Genet. 1988 Jan.

Abstract

X-linked nephrogenic diabetes insipidus (NDI) was segregating in a large Indiana family. It was tested for linkage of the NDI gene to X-chromosome molecular markers. Maximum lod scores of 3.15 and 3.01 (theta = 0) obtained for the molecular markers F8A (F8C) and DXS15 (DX13) respectively, indicate that the NDI gene is located in Xq28. A lod score of 3.61 (theta = 0) was obtained with multipoint linkage analysis of F8A and DXS15.

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