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Review
. 2017 Sep 5:6:1645.
doi: 10.12688/f1000research.11682.1. eCollection 2017.

Dysmenorrhea and related disorders

Mariagiulia Bernardi  1 , Lucia Lazzeri  1 , Federica Perelli  2 , Fernando M Reis  3 , Felice Petraglia  2
Affiliations
Review

Dysmenorrhea and related disorders

Mariagiulia Bernardi et al. F1000Res. .

Abstract

Dysmenorrhea is a common symptom secondary to various gynecological disorders, but it is also represented in most women as a primary form of disease. Pain associated with dysmenorrhea is caused by hypersecretion of prostaglandins and an increased uterine contractility. The primary dysmenorrhea is quite frequent in young women and remains with a good prognosis, even though it is associated with low quality of life. The secondary forms of dysmenorrhea are associated with endometriosis and adenomyosis and may represent the key symptom. The diagnosis is suspected on the basis of the clinical history and the physical examination and can be confirmed by ultrasound, which is very useful to exclude some secondary causes of dysmenorrhea, such as endometriosis and adenomyosis. The treatment options include non-steroidal anti-inflammatory drugs alone or combined with oral contraceptives or progestins.

Keywords: Dysmenorrhea; adenomyosis; endometriosis; menstrual disorders.

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Conflict of interest statement

Competing interests: The authors declare that they have no competing interests.No competing interests were disclosed.No competing interests were disclosed.No competing interests were disclosed.

Figures

Figure 1.
Figure 1.. Flowchart for the management of patients with dysmenorrhea.
Flowchart for the management of patients with dysmenorrhea.
See this image and copyright information in PMC

References

    1. Hanoch Kumar K, Elavarasi P: Definition of pain and classification of pain disorders. Journal of Advanced Clinical & Research Insight. 2016;3:87–90. 10.15713/ins.jcri.112 - DOI
    1. ACOG Committee on Practice Bulletins--Gynecology: ACOG Practice Bulletin No. 51. Chronic pelvic pain. Obstet Gynecol. 2004;103(3):589–605. - PubMed
    1. Patel V, Tanksale V, Sahasrabhojanee M, et al. : The burden and determinants of dysmenorrhoea: a population-based survey of 2262 women in Goa, India. BJOG. 2006;113(4):453–63. 10.1111/j.1471-0528.2006.00874.x - DOI - PubMed
    1. Harlow SD, Campbell OM: Epidemiology of menstrual disorders in developing countries: a systematic review. BJOG. 2004;111(1):6–16. 10.1111/j.1471-0528.2004.00012.x - DOI - PubMed
    1. Weissman AM, Hartz AJ, Hansen MD, et al. : The natural history of primary dysmenorrhoea: a longitudinal study. BJOG. 2004;111(4):345–52. 10.1111/j.1471-0528.2004.00090.x - DOI - PubMed