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. 2017 Sep 11;4(1):e000153.
doi: 10.1136/bmjgast-2017-000153. eCollection 2017.

Weight regain after Roux-en-Y gastric bypass has a large negative impact on the Bariatric Quality of Life Index

Pichamol Jirapinyo  1   2 , Barham K Abu Dayyeh  3 , Christopher C Thompson  1   2
Affiliations

Weight regain after Roux-en-Y gastric bypass has a large negative impact on the Bariatric Quality of Life Index

Pichamol Jirapinyo et al. BMJ Open Gastroenterol. .

Abstract

Background: Despite initial successful weight loss, some patients may experience weight regain following Roux-en-Y gastric bypass (RYGB).

Objective: To assess the impact of weight regain on bariatric patients' quality of life (QoL).

Methods: This was a prospective cross-sectional study. Fifty-six consecutive RYGB patients were recruited and divided into weight-regain and weight-stable cohorts. QoL was assessed using the Bariatric Quality of Life (BQL) questionnaire. The BQL Index scores of the weight-regain and weight-stable groups were compared using Student's t-test. Additionally, the BQL Index score of the weight-regain group was compared with that of historical prebariatric patients. Predictors of BQL were assessed using univariate and multivariate linear regression analyses.

Results: Of 56 RYGB patients, 41 (73%) had weight regain. On average, patients had body mass index (BMI) of 37 ±7.5 kg/m2 and gained 34 ±26% of maximal weight initially lost. Weight-regain patients had lower BQL Index scores than weight-stable patients (44.8±6 vs 53±7, p<0.001). Patients with weight regain had similar BQL Index scores as the prebariatric patients despite lower BMI (BMI of 39.7±6.8 vs 47.2±7.6, p<0.05; BQL Index of 44.8±6 vs 41.6±10.4, p=0.144, respectively). Years from RYGB, BMI and amount of weight regain were associated with BQL Index on a univariate analysis (β=-0.55,-0.52, -0.7; p<0.0001). Only weight regain was a significant predictor of BQL on a multivariate analysis (β =-0.56; p=0.001).

Conclusion: Weight regain had a negative impact on bariatric patients' QoL. Patients who regained at least 15% of maximal weight lost appeared to have as low QoL as those who had not undergone bariatric surgery despite a lower BMI.

Keywords: BQL; HRQL; RYGB; bariatric surgery; quality of life; weight regain.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
The Bariatric Quality of Life questionnaire (part 1). From Weiner et al.
Figure 2
Figure 2
The Bariatric Quality of Life questionnaire (part 2). From Weiner et al
Figure 3
Figure 3
Amount of weight regain in patients who were <5, 5–10 and >10 years post-RYGB. RYGB, Roux-en-Y gastric bypass.
Figure 4
Figure 4
Scatter plot with best-fit linear regression line and 95% CI of the association between weight regain and Bariatric Quality of Life (BQL) Index scores.
See this image and copyright information in PMC

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