Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2017 Jul 14;9(7):e1470.
doi: 10.7759/cureus.1470.

A Case of Renal Metastasis of Uterine Leiomyosarcoma

Petar Bajic  1 , William S Gange  2 , Robert H Blackwell  3 , Arpeet S Shah  1 , John Biemer  4 , Maria M Picken  4 , Alex Gorbonos  1
Affiliations
Case Reports

A Case of Renal Metastasis of Uterine Leiomyosarcoma

Petar Bajic et al. Cureus. .

Abstract

A 49-year-old woman with a distant history of uterine leiomyosarcoma underwent robotic-assisted laparoscopic partial nephrectomy for a 3.5 cm right renal mass, which was presumed to be a primary renal cell carcinoma. Surgical margins were negative, and the histologic analysis confirmed leiomyosarcoma. Uterine leiomyosarcoma is traditionally a locally aggressive disease with only rare reports of renal involvement. We report a case of a metastatic leiomyosarcoma to the kidney four years following initial treatment for uterine leiomyosarcoma.

Keywords: desmin; kidney; leiomyosarcoma; metastasis; partial nephrectomy; smooth muscle actin.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Representative contrast computed tomographic images of the renal mass
A) axial and B) sagittal planes
Figure 2
Figure 2. Histologic slides from the tumor specimen
See this image and copyright information in PMC

References

    1. Treatment of uterine sarcomas. Echt G, Jepson J, Steel J, et al. Cancer. 1990;66:35–39. - PubMed
    1. Prognostic factors and survival in 1396 patients with uterine leiomyosarcomas. Kapp DS, Shin JY, Chan JK. Cancer. 2008;112:820–830. - PubMed
    1. Prognostic factors and treatment outcomes of patients with uterine sarcoma: analysis of 127 patients at a single institution, 1989-2007. Park JY, Kim DY, Suh DS, et al. J Cancer Res Clin Oncol. 2008;134:1277–1287. - PubMed
    1. NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®): Uterine Neoplasms, version 2.2016. [Jul;2017 ];Cancer Cancer. http://www.tri-kobe.org/nccn/guideline/gynecological/english/uterine.pdf National Comprehensive Care Network. 2016 2
    1. Prognostic factors in early-stage uterine sarcoma: a Gynecologic Oncology Group study. Major FJ, Blessing JA, Silverberg SG, et al. Cancer. 1993;71:1702–1709. - PubMed

Publication types

LinkOut - more resources