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Case Reports
. 2017 Aug;6(3):215-218.
doi: 10.5582/irdr.2017.01041.

Filarial huge splenomegaly dramatically regressed by anti-filarial medication: A rare clinical scenario

Ayan Basu  1 , Arvind Kumar  1 , Smita Manchanda  2 , Naveet Wig  1
Affiliations
Case Reports

Filarial huge splenomegaly dramatically regressed by anti-filarial medication: A rare clinical scenario

Ayan Basu et al. Intractable Rare Dis Res. 2017 Aug.

Abstract

Lymphatic filariasis is caused by nematodes Wuchereria bancrofti, Brugia malayi and Brugia timori. Lymphatic filariasis is a spectrum of illness and can manifest as, asymptomatic microfilaraemia, acute lymphatic filariasis (lymphangitis and lymphoedema), chronic lymphoedema, elephantiasis, hydrocele, tropical pulmonary eosinophilia and some systemic manifestations which involves joint, heart, kidney, nerve, etc. We here present a case of huge splenomegaly caused by lymphatic filariasis which is a rare presentation and only few cases had been reported in the world literature so far. After treatment of filariasis spleen size was reduced dramatically and patient is doing well even after 6 months of follow up after therapy.

Keywords: Filariasis; lymphatic; splenomegaly.

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Figures

Figure 1.
Figure 1.
(A) Baseline ultrasound reveals gross splenomegaly (size 20.1 cm) and (B) CECT coronal reformatted image reveals the markedly enlarged (22 cm), homogenous spleen (arrow).
Figure 2.
Figure 2.
Microscopic finding. (A & B) Microfilariae of Wuchereria bancrofti in bone marrow.
Figure 3.
Figure 3.
Ultrasonography done at 5th day (A) and end of the treatment (B) showed reduction of splenomegaly (16.24 cm and 12.5 cm respectively).
See this image and copyright information in PMC

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