Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Sep 18;10(9):1385-1391.
doi: 10.18240/ijo.2017.09.09. eCollection 2017.

Influence of corneal power on circumpapillary retinal nerve fiber layer and optic nerve head measurements by spectral-domain optical coherence tomography

Kazunori Hirasawa  1 , Nobuyuki Shoji  2
Affiliations

Influence of corneal power on circumpapillary retinal nerve fiber layer and optic nerve head measurements by spectral-domain optical coherence tomography

Kazunori Hirasawa et al. Int J Ophthalmol. .

Abstract

Aim: To evaluate the influence of corneal power on circumpapillary retinal nerve fiber layer (cpRNFL) and optic nerve head (ONH) measurements by spectral-domain optical coherence tomography (SD-OCT).

Methods: Twenty-five eyes of 25 healthy participants (mean age 23.6±3.6y) were imaged by SD-OCT using horizontal raster scans. Disposable soft contact lenses of different powers (from -11 to +5 diopters including 0 diopter) were worn to induce 2-diopter changes in corneal power. Differences in the cpRNFL and ONH measurements per diopter of change in corneal power were analyzed.

Results: As corneal power increased by 1 diopter, total and quadrant cpRNFL thicknesses, except for the nasal sector, decreased by --0.19 to -0.32 µm (P<0.01). Furthermore, the disc, cup, and rim areas decreased by -0.017, -0.007, and -0.015 mm2, respectively (P<0.001); the cup and rim volumes decreased by -0.0013 and -0.006 mm3, respectively (P<0.01); and the vertical and horizontal disc diameters decreased by -0.006 and -0.007 mm, respectively (P<0.001).

Conclusion: For more precise OCT imaging, the ocular magnification should be corrected by considering both the axial length and corneal power. However, the effect of corneal power changes on cpRNFL thickness and ONH topography are small when compare with those of the axial length.

Keywords: circumpapillary retinal nerve fiber layer; corneal power; ocular magnification; optic nerve head; optical coherence tomography.

PubMed Disclaimer

Figures

Figure 1
Figure 1. Actual (A) and percent (B) changes in total cpRNFL thickness induced by increasing corneal power using soft contact lenses.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Leung CK, Cheung CY, Weinreb RN, Qiu Q, Liu S, Li H, Xu G, Fan N, Huang L, Pang CP, Lam DS. Retinal nerve fiber layer imaging with spectral-domain optical coherence tomography: a variability and diagnostic performance study. Ophthalmology. 2009;116(7) - PubMed
    1. Mwanza JC, Chang RT, Budenz DL, Durbin MK, Gendy MG, Shi W, Feuer WJ. Reproducibility of peripapillary retinal nerve fiber layer thickness and optic nerve head parameters measured with cirrus HD-OCT in glaucomatous eyes. Invest Ophthalmol Vis Sci. 2010;51(11):5724–5730. - PMC - PubMed
    1. Garcia-Martin E, Pinilla I, Idoipe M, Fuertes I, Pueyo V. Intra and interoperator reproducibility of retinal nerve fibre and macular thickness measurements using Cirrus Fourier-domain OCT. Acta Ophthalmol. 2011;89(1):e23–e29. - PubMed
    1. Kim JS, Ishikawa H, Sung KR, Xu J, Wollstein G, Bilonick RA, Gabriele ML, Kagemann L, Duker JS, Fujimoto JG, Schuman JS. Retinal nerve fibre layer thickness measurement reproducibility improved with spectral domain optical coherence tomography. Br J Ophthalmol. 2009;93(8):1057–1063. - PMC - PubMed
    1. Carpineto P, Nubile M, Agnifili L, Toto L, Aharrh-Gnama A, Mastropasqua R, Di Antonio L, Fasanella V, Mastropasqua A. Reproducibility and repeatability of CirrusTM HD-OCT peripapillary retinal nerve fibre layer thickness measurements in young normal subjects. Ophthalmologica. 2012;227(3):139–145. - PubMed

LinkOut - more resources