Manifestations of sickle cell disease on thoracic imaging

Abstract

Sickle cell disease is an inherited hemolytic disease with systemic complications. These complications significantly impact the patients' quality of life. There are characteristic radiological findings that can aid in the diagnosis and management of common sequelae of sickle cell disease. In this review, we will discuss the thoracic imaging findings of common complications of sickle cell disease in an organ-based approach and provide imaging examples of them.

Keywords: Acute chest syndrome; Autoinfarction; Computed tomography; Osteonecrosis; Pulmonary embolism; Sickle cell disease; Thoracic imaging.