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Multicenter Study
. 2017 Sep 24;7(9):e013427.
doi: 10.1136/bmjopen-2016-013427.

Discrepancies in drug histories at admission to gastrointestinal surgery, internal medicine and geriatric hospital wards in Central Norway: a cross-sectional study

Affiliations
Multicenter Study

Discrepancies in drug histories at admission to gastrointestinal surgery, internal medicine and geriatric hospital wards in Central Norway: a cross-sectional study

Janne Kutschera Sund et al. BMJ Open. .

Abstract

Objectives: To compare discrepancies in drug histories among patients acutely admitted to different hospital wards, classify the discrepancies according to their potential clinical impact and identify appropriate selection criteria for patients that should be subject to a detailed drug history at admission.

Design: Cross-sectional study.

Setting: Two gastrointestinal surgery wards and one geriatric ward at St Olav's University Hospital in Trondheim and two general internal medicine wards at Ålesund Hospital in Ålesund, Norway.

Participants: All patients acutely admitted to these wards during a period of three months were asked to participate in the study. A total of 168 patients were included. For each patient, drug information available at admission was compared with information from drug lists obtained from the general practitioner and (if applicable) the home care services/the nursing home.

Primary and secondary outcome measures: Number of patients with one or more discrepancies in their drug history. Type and clinical impact of the discrepancies found. Selection criteria for patients that should be subject to a detailed drug history.

Results: In total, 83% had at least one discrepancy in their drug history. Omission of a drug accounted for 72% of the discrepancies, whereas a difference in dosing was the cause of the remaining 28%. 9% of the discrepancies had the potential to cause severe harm or discomfort. We found no significant differences in the number of discrepancies between hospital wards, genders, ages or levels of care.

Conclusions: This study demonstrates the importance of collecting drug information from all available sources when a patient is admitted to hospital. As we found no significant differences in discrepancies between subgroups of patients, we suggest that medication reconciliation should be performed for all patients.

Keywords: clinical pharmacology; geriatric medicine; internal medicine; medication reconciliation; quality in health care; surgery.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Distribution of patients according to the total number of discrepancies found when comparing the drug list from the hospital record with all other available sources of information.
Figure 2
Figure 2
Drugs prescribed for 20 patients or more sorted by the percentage of prescriptions with discrepancies.

References

    1. Chhabra PT, Rattinger GB, Dutcher SK, et al. . Medication reconciliation during the transition to and from long-term care settings: a systematic review. Res Social Adm Pharm 2012;8:60–75. 10.1016/j.sapharm.2010.12.002 - DOI - PubMed
    1. Cornish PL, Knowles SR, Marchesano R, et al. . Unintended medication discrepancies at the time of hospital admission. Arch Intern Med 2005;165:424–9. 10.1001/archinte.165.4.424 - DOI - PubMed
    1. Hellström LM, Bondesson Å, Höglund P, et al. . Errors in medication history at hospital admission: prevalence and predicting factors. BMC Clin Pharmacol 2012;12:9 10.1186/1472-6904-12-9 - DOI - PMC - PubMed
    1. Tam VC, Knowles SR, Cornish PL, et al. . Frequency, type and clinical importance of medication history errors at admission to hospital: a systematic review. CMAJ 2005;173:510–5. 10.1503/cmaj.045311 - DOI - PMC - PubMed
    1. Gjerde AM, Aa E, Sund JK, et al. . Medication reconciliation of patients with hip fracture by clinical pharmacists Eur J Hosp Pharm 2016;23:166–70. - PMC - PubMed

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