Vitamin D supplementation
- PMID: 28947637
- DOI: 10.1136/practneurol-2017-001720
Vitamin D supplementation
Abstract
Vitamin D testing and supplementation is of great interest to neurologists and their patients. Recommended nutritional intakes of vitamin D in the UK remain focused on bone health, despite increasing evidence for a role outside this area. Here we discuss how neurologists might approach vitamin D testing and supplementation, focusing on two conditions associated with vitamin D deficiency that have an increased risk of downstream complications resulting from these: multiple sclerosis and epilepsy. We set out a rationale for testing serum 25-hydroxyvitamin D concentrations and discuss our personal practice in terms of supplementation, with evidence where available.
Keywords: epilepsy; multiple sclerosis; osteoporosis; supplementation; vitamin D.
© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
Conflict of interest statement
Competing interests: RD has received sponsorship to attend conferences from Biogen Idec, Novartis, Teva and Sanofi Genzyme. She has received speaking honoraria from Teva. HRC reports personal fees from UCB Pharma, Epilepsy Nurse Specialist Association UK, European Medicines Agency, Special Products and Eisai Europe; non-financial support from GSK; personal fees and non-financial support from Lupin Pharmaceuticals; and grants from NINDS, NIH USA, outside the submitted work. GG has received consultation and speaking fees from Biogen-Idec, GSK, Merck-Serono, Novartis, Genzyme-Sanofi and Synthon BV. He is on the steering committee for studies sponsored by AbbVie, Biogen-Idec, Novartis, Teva and Roche.
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