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. 2017 Oct;25(10):1691-1698.
doi: 10.1002/oby.21968.

The Primary Results of the Treating Adult Smokers at Risk for Weight Gain with Interactive Technology (TARGIT) Study

Karen C Johnson  1 , Fridtjof Thomas  1 , Phyllis Richey  1 , Quynh T Tran  1 , Fran Tylavsky  1 , Danielle Miro  2 , Mace Coday  1
Affiliations

The Primary Results of the Treating Adult Smokers at Risk for Weight Gain with Interactive Technology (TARGIT) Study

Karen C Johnson et al. Obesity (Silver Spring). 2017 Oct.

Abstract

Objective: To evaluate whether a behavioral weight management program combined with a smoking cessation program delivered via interactive technology could prevent postcessation weight gain.

Methods: Three hundred and thirty young adult smokers, age 18 to 35 years, were randomized to a smoking cessation program alone (comparison group), which included behavioral counseling and nicotine replacement, or to a behavioral weight management program adapted from the Look AHEAD trial plus the same smoking cessation program (intervention group).

Results: The Treating Adult Smokers at Risk for Weight Gain with Interactive Technology study randomized 164 participants to the comparison group and 166 participants to the intervention group. On average, the participants gained 0.91 kg after 24 months in the trial (comparison group + 1.45 kg and intervention group + 0.32; P = 0.157). The only variable systematically affecting weight change over time was smoking abstinence, in which those who were abstinent, on average, gained 0.14 kg more per month compared with those who continued to smoke (P < 0.001). In exploratory analyses, the intervention participants who were abstinent at 6 months had numerically smaller weight gains compared with abstinent participants in the comparison group, but these differences were not statistically significant.

Conclusions: Providing an intensive weight gain prevention program combined with a smoking cessation program via interactive technology was not associated with greater long-term weight gain prevention.

Trial registration: ClinicalTrials.gov NCT01199185.

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Conflict of interest statement

Disclosure: The authors declared no conflict of interest

Figures

Figure 1
Figure 1
TARGIT Consort Diagram
Figure 2
Figure 2
Weight Change by Treatment Assignment
Figure 3
Figure 3
Smoking Cessation Rates by Treatment Assignment
Figure 4
Figure 4
Weight Change by 6 Month Smoking Status by Treatment Assignment
See this image and copyright information in PMC

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