From clinical epidemiology to practice recommendations: Knowledge gaps and uncertainty in the management of anal precancers
- PMID: 28949415
- PMCID: PMC8771459
- DOI: 10.1002/cncr.31033
From clinical epidemiology to practice recommendations: Knowledge gaps and uncertainty in the management of anal precancers
Abstract
We discuss the existing data on anal precancers and demonstrate the impact of evidence gaps and uncertainty on a clinical decision model developed to provide clinical guidance for management of anal precancers.
Keywords: Anal precancer; clinical epidemiology; clinical recommendations; cost effectiveness; uncertainty.
Conflict of interest statement
Comment on
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Management of precancerous anal intraepithelial lesions in human immunodeficiency virus-positive men who have sex with men: Clinical effectiveness and cost-effectiveness.Cancer. 2017 Dec 1;123(23):4709-4719. doi: 10.1002/cncr.31035. Epub 2017 Sep 26. Cancer. 2017. PMID: 28950043 Free PMC article.
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