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. 2017 Sep 25;27(18):R1017-R1020.
doi: 10.1016/j.cub.2017.07.065.

Structural Biology: A Force-Sensitive Ion Channel Springs to Life

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Structural Biology: A Force-Sensitive Ion Channel Springs to Life

Xin Liang et al. Curr Biol. .
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Abstract

The sensations of sound, acceleration and touch are mediated by mechanotransduction channels, which convert mechanical stimuli into electrical responses. The structure of one such channel, NOMPC, was recently solved by cryo-EM, revealing a bundle of helices that may act as coiled springs to transmit the forces that open the channel.

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