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Case Reports
. 2017 Sep 25:2017:bcr2017222141.
doi: 10.1136/bcr-2017-222141.

Digital ischaemia after intra-arterial drug injection

Affiliations
Case Reports

Digital ischaemia after intra-arterial drug injection

Michael James Neuss et al. BMJ Case Rep. .
No abstract available

Keywords: drug misuse (including addiction); pain; pathology; vasculitis.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Photograph of left hand showing digital necrosis, prior thumb and index finger partial amputations, and mottling of the palm.
Figure 2
Figure 2
Three-dimensional reconstruction of left upper extremity CT angiography. The radial artery (long arrow) is obstructed and the ulnar artery (short arrow) is hypertrophied. There is poor flow through the superficial palmar arch (arrowhead).
Figure 3
Figure 3
H&E-stained histological section from a specimen of left radial artery, showing polarisable microcrystalline cellulose pill filler material embedded in remote and subacute thrombus.

References

    1. Hedden SL, Kennet J Lipari R, et al. Center for Behavioral Health Statistics and Quality. Behavioral health trends in the United States: results from the 2014 National Survey on Drug Use and Health. 2015. HHS Publication No SMA 15-Page 2 of 52.3.4927, NSDUH Series H-50 http://www.samhsa.gov/data/
    1. Chang MY, Lin JL. Irreversible ischemic hand following intraarterial injection of zolpidem powder. J Toxicol Clin Toxicol 2003;41:1025–8. doi:10.1081/CLT-120026529 - DOI - PubMed
    1. Dowell D, Haegerich T, Chou R. CDC Guideline for Prescribing Opioids for Chronic Pain - United States, 2016. MMWR Recomm Rep 201665:1–49. - PubMed

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