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. 2017 Nov;70(11):1047-1052.
doi: 10.1038/ja.2017.105. Epub 2017 Sep 27.

Pteridic acids C-G spirocyclic polyketides from the marine-derived Streptomyces sp. SCSGAA 0027

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Pteridic acids C-G spirocyclic polyketides from the marine-derived Streptomyces sp. SCSGAA 0027

Xu-Hua Nong et al. J Antibiot (Tokyo). 2017 Nov.

Abstract

Five new pteridic acids C-G (1-5) were isolated from a culture broth of the marine-derived actinomycete Streptomyces sp. SCSGAA 0027. Their complete structures were elucidated on the basis of NMR data, modified Mosher's method and quantum chemical calculations. Furthermore, their cytotoxicity, antiviral and antimicrobial activities were also evaluated.

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