Concomitant poroma and porocarcinoma

Abstract

Eccrine poromas and porocarcinomas are adnexal tumors derived from the sweat duct epithelium. However, eccrine poroma is benign in nature, whilst eccrine porocarcinoma is regarded as its malignant counterpart. We report the case of a man who presented simultaneously with an eccrine poroma and eccrine porocarcinoma. Both lesions had no clear distinctive features, enhancing the need of high-level clinical suspicion together with surgical excision and histopathology for prompt diagnosis confirmation.

Figure 1

Eccrine poroma. Erythematous to violaceous dome-shaped nodule located on the chest

Figure 2

Eccrine porocarcinoma

Figure 3 A and B

Histopathology of Eccrine poroma. Nests of uniform small cuboidal poroid cells with monomorphic nuclei and narrow duct-like lumina lined by eosinophilic cuticles (A: Hematoxylin & eosin stain, X40. B: Hematoxylin & eosin, X100)

Figure 4 A and B

Histopathology of Eccrine porocarcinoma. Lobular infiltrative tumor composed of small cuboidal cells forming ductal lumina that extended into the dermis. Closer examination reveals atypical neoplastic cells with hyperchromatic nuclei and some mitotic figures (A: Hematoxylin & eosin stain, X40. B: Hematoxylin & eosin stain, X100)