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Case Reports
. 2017 Jul-Aug;92(4):571-572.
doi: 10.1590/abd1806-4841.20175211.

Do you know this syndrome? Heerfordt-Waldenström syndrome

Rafael Cavanellas Fraga  1 , Priscila Kakizaki  2 , Neusa Yuriko Sakai Valente  2 , Larissa Karine Leite Portocarrero  2 , Mônica Fernandes Senise Teixeira  2 , Priscilla Fernandes Senise  3
Affiliations
Case Reports

Do you know this syndrome? Heerfordt-Waldenström syndrome

Rafael Cavanellas Fraga et al. An Bras Dermatol. 2017 Jul-Aug.

Abstract

Heerfordt-Waldenström syndrome is a rare subacute variant of sarcoidosis, characterized by enlargement of the parotid or salivary glands, facial nerve paralysis and anterior uveitis. Granulomas with a peripheral lymphocyte deficit are found in the anatomic pathology of affected organs. It is normally self-limiting, with cure achieved between 12 and 36 months, but some prolonged cases have been reported. Diagnosis of the syndrome is clinical, and treatment depends on the degree of systemic impairment. Oral corticosteroids represent the first line treatment option. The mortality rate ranges between 1 and 5% of cases.

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Conflict of interest statement

Conflict of interest: none.

Figures

Figure 1
Figure 1
Papule on the forehead, with a translucent appearance and red-brownish color
Figure 2
Figure 2
Conjunctival hyperemia secondary to uveitis
Figure 3
Figure 3
Sarcoidal granulomas on the dermis (left photo, hematoxylin and eosin, X100). Presence of multinucleated cells in the granuloma (right photo, hematoxylin and eosin, X400)
See this image and copyright information in PMC

References

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