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Case Reports
. 2017 Jul-Aug;92(4):591-593.
doi: 10.1590/abd1806-4841.20176481.

Biologic therapy-induced pemphigus

Affiliations
Case Reports

Biologic therapy-induced pemphigus

Marina Zoega Hayashida et al. An Bras Dermatol. 2017 Jul-Aug.
No abstract available

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Conflict of interest statement

Conflict of interests: None.

Figures

Figure 1
Figure 1
A) Erythematous scaly papules and plaques, with some superficial ulcerations on the neckline; B) Improvement after treatment.
Figure 2
Figure 2
A) Focal area with suprabasal acantholysis, involving the follicular epithelium, besides acanthosis and crust with fibrin and leukocytes (HE, X100); B) Immunohistochemistry with expression of intercellular IgG; C) Immunohistochemistry with expression of intercellular C3.

References

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    1. Landau M, Brenner S. Histopathologic findings in drug-induced pemphigus. Am J Dermatopathol. 1997;19:411–414. - PubMed
    1. Baroni A, Russo T, Faccenda F, Piccolo V. Amoxicillin/Clavulanic Acid-Induced Pemphigus Vulgaris: Case Report. Acta Dermatovenerol Croat. 2012;20:108–111. - PubMed
    1. Genovese MC, Greenwald MW, Cho CS, Berman A, Jin L, Cameron G. A Phase 2 Study of Multiple Subcutaneous Doses of LY2439821, An Anti-IL-17 Monoclonal Antibody, in Patients with Rheumatoid Arthritis in Two Populations: Naïve to Biologic Therapy or Inadequate Responders to Tumor Necrosis Factor Alpha Inhibitors; ACR meeting; Chicago. 2011.
    1. Cosentyx (secukinumab) [prescribing information] East Hanover, NJ: Novartis Pharmaceuticals Corp; 2016.

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