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Case Reports
. 2017 Sep 27:2017:bcr2017221454.
doi: 10.1136/bcr-2017-221454.

Dementia with Lewy bodies presenting as probable epileptic seizure

Affiliations
Case Reports

Dementia with Lewy bodies presenting as probable epileptic seizure

Mya Z Tun et al. BMJ Case Rep. .

Abstract

We discuss the case of an 83-year-old man admitted to the hospital after losing control of his vehicle due to an unexplained episode of altered consciousness. This occurred on a background of multiple similar episodes associated with acute confusion, superimposed on a gradual cognitive decline spanning 6 years. Organic aetiologies for delirium were excluded and CT and MRI of the brain were negative for cerebrovascular accidents or other epileptogenic foci. Electroencephalogram (EEG) was negative for epileptiform activity. A diagnosis of seizure in the setting of dementia with Lewy bodies (DLB) was deemed probable. Subsequent brain single-photon emission computed tomography (SPECT) and flurodeoxy glucose-positron emission tomography (FDG-PET) studies supported the underlying diagnosis of DLB. Acute changes in consciousness or cognition are often related to strokes or seizures in the older person. As illustrated in this case, however, it is important to consider alternative comorbidities that may coexist.

Keywords: dementia, alzheimer’s type; epilepsy and seizures; geriatric medicine; memory disorders (psychiatry).

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Conflict of interest statement

Competing interests: None declared.

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References

    1. García-Cabrero AM, Guerrero-López R, Giráldez BG, et al. . Hyperexcitability and epileptic seizures in a model of frontotemporal dementia. Neurobiol Dis 2013;58:200–8. 10.1016/j.nbd.2013.06.005 - DOI - PubMed
    1. Hauser WA, Morris ML, Heston LL, et al. . Seizures and myoclonus in patients with Alzheimer’s disease. Neurology 1986;36:1226 10.1212/WNL.36.9.1226 - DOI - PubMed
    1. Bernardi S, Scaldaferri N, Vanacore N, et al. . Seizures in Alzheimer’s disease: a retrospective study of a cohort of outpatients. Epileptic Disord 2010;12:16–21. 10.1684/epd.2010.0290 - DOI - PubMed
    1. Romanelli MF, Morris JC, Ashkin K, et al. . Advanced Alzheimer’s disease is a risk factor for late-onset seizures. Arch Neurol 1990;47:847–50. 10.1001/archneur.1990.00530080029006 - DOI - PubMed
    1. Scarmeas N, Honig LS, Choi H, et al. . Seizures in Alzheimer disease: who, when, and how common? Arch Neurol 2009;66:992–7. 10.1001/archneurol.2009.130 - DOI - PMC - PubMed

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