Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1988 Jan 22;232(1269):367-73.
doi: 10.1098/rspb.1988.0001.

Alzheimer's disease: coated vesicles, coated pits and the amyloid-related cell

A Roher  1 , E G Gray, M Paula-Barbosa
Affiliations

Alzheimer's disease: coated vesicles, coated pits and the amyloid-related cell

A Roher et al. Proc R Soc Lond B Biol Sci. .

Abstract

The amyloid-related cell (ARC) of the neuritic plaques of Alzheimer's disease revealed numerous cytoplasmic projections surrounding extracellular amyloid material. It is proposed that ARC-coated vesicles fuse with the cell membrane, forming coated pits, which may empty their secretory material into the extracellular space where polymerization of amyloid filaments could occur.

PubMed Disclaimer

Publication types

LinkOut - more resources