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Review
. 2017 Sep 14;3(2):e000484.
doi: 10.1136/rmdopen-2017-000484. eCollection 2017.

Pneumococcal vaccination in autoimmune rheumatic diseases

Éva Rákóczi  1   2 , Zoltan Szekanecz  2
Affiliations
Review

Pneumococcal vaccination in autoimmune rheumatic diseases

Éva Rákóczi et al. RMD Open. .

Abstract

Streptococcus pneumoniae is the leading cause of the community-acquired pneumonia. The mortality rate of invasive pneumococcal infections is high. Immunocompromised patients suffering from autoimmune inflammatory rheumatic diseases (AIRD) have a high risk for acquiring these infections. Protection against infection can be improved with vaccination. After using polysaccharide vaccines (PPV-23), in July 2013, a 13-valent conjugate vaccine (PCV-13) was approved for adults. Due to its conjugate form, this vaccine is the recommended choice in pneumococcal vaccine-naive patients. PCV-13 is also recommended in patients previously receiving PPV-23. Vaccination in AIRD is very important and needs deliberate scheduling to coordinate with the immunosuppressive therapy. Here, based on international and national vaccine guidelines, we provide a current review of PPV-23 and PCV-13 vaccines for specialists following patients with AIRD.

Keywords: infections; rheumatoid arthritis; vaccination.

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Conflict of interest statement

Competing interests: None declared.

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