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Review
. 2016 Jan 12;50(1):59-64.
doi: 10.17096/jiufd.24812. eCollection 2016.

Bisphosphonate-related osteonecrosis of the jaw and dental implants

Ala Hassan A Qamheya  1 , Sinem Yeniyol  1 , Volkan Arisan  1
Affiliations
Review

Bisphosphonate-related osteonecrosis of the jaw and dental implants

Ala Hassan A Qamheya et al. J Istanb Univ Fac Dent. .

Abstract

Bisphosphonate (BP) is one of the possible riskfactors in the osteonecrosis of the jaw (ON J). Surgical interventions during or after the course of treatment by using BPs may expose the patient under this risk. Animal studies, human studies, case reports, and systematic reviews are used to show the relationship between the use of bisphosphonates and dental implants. In this review data about bisphosphonaterelated osteonecrosis of the jaw (BRON J): incidence, prevention and treatment modalities for the patients who are scheduled for dental implant treatment plan and who have been already treated by dental implants will be investigated. Various views for the relationship between dental implants and bisphosphonates will be analyzed depending on the multifactors: duration, route of uptake, dosage of the drug and patient's other medications that affect the effects of bisphosphonate. All patients treated with this drug must be informed about the risk of implant loss or possibility of osteonecrosis.

Keywords: BRONJ treatment; Bisphosphonate-related osteonecrosis of the jaw (BRONJ); dental implants; risk factors.

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Conflict of interest statement

Conflict of interest: None declared.

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