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Comment
. 2017 Oct:24:5-6.
doi: 10.1016/j.ebiom.2017.09.026. Epub 2017 Sep 21.

Contributions of the Intrinsic Mutation Process to Cancer Mutation and Risk Burdens

Wei Zhu  1 , Song Wu  2 , Yusuf A Hannun  3
Affiliations
Comment

Contributions of the Intrinsic Mutation Process to Cancer Mutation and Risk Burdens

Wei Zhu et al. EBioMedicine. 2017 Oct.
No abstract available

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Figures

Fig. 1
Fig. 1
The (conservative non-zero) minimum, the 10th and 90th percentiles, the US average, and the maximum of the lifetime cancer risk based on World cancer registry, and the stem-cell-model based minimum. The huge disparity between the US average and world minimum indicates that cancer is unlikely the end result of a universal endogenous carcinogenesis mechanism unaffected by exogenous factors.
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