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Review
. 2016 Feb 16;1(1):23-27.
doi: 10.1136/svn-2015-000003. eCollection 2016 Mar.

Mechanisms of hydrocephalus after intraventricular haemorrhage in adults

Yaoyao Bu  1 , Meiyuan Chen  1 , Ting Gao  1 , Xiao Wang  1 , Xuting Li  1 , Feng Gao  1
Affiliations
Review

Mechanisms of hydrocephalus after intraventricular haemorrhage in adults

Yaoyao Bu et al. Stroke Vasc Neurol. .

Abstract

Intraventricular haemorrhage (IVH) is defined as the eruption of blood in the cerebroventricular system and occurs mostly secondary to intracerebral haemorrhage (ICH) in adults. Hydrocephalus is a severe complication of IVH that can serve as an independent predictor of increased mortality. In this mini-review, we focus on the mechanisms of hydrocephalus after adult IVH, including blood-clot blockage, barrier impairment, inflammation and blood components, and attempt to reconcile the current research findings into a unified framework. We expect our theoretical framework to help guide future clinical and basic research leading to improved monitoring and intervention for IVH and subsequent hydrocephalus.

Keywords: Brain; Hemorrhage; Hydrocephalus; Inflammation; Ventricle.

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Conflict of interest statement

Competing interests: None declared.

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