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. 2017 Nov;14(11):1024-1025.
doi: 10.1038/nmeth.4462. Epub 2017 Sep 28.

The Experimental Design Assistant

Nathalie Percie du Sert  1 , Ian Bamsey  2 , Simon T Bate  3 , Manuel Berdoy  4 , Robin A Clark  5 , Innes C Cuthill  6 , Derek Fry  7 , Natasha A Karp  8   9 , Malcolm Macleod  10 , Lawrence Moon  11 , S Clare Stanford  12 , Brian Lings  2
Affiliations

The Experimental Design Assistant

Nathalie Percie du Sert et al. Nat Methods. 2017 Nov.
No abstract available

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Conflict of interest statement

Competing Financial Interests

The authors declare no competing financial interests.

Figures

Figure 1
Figure 1. Example of an EDA diagram.
EDA diagram representing a two-group comparison in which each cage contains mice randomized to either of two treatments. Diagrams are composed of nodes and links to represent an entire experimental plan. The gray nodes contain high-level information about the experiment such as the null and alternative hypotheses, the effect of interest, the experimental unit and the animal characteristics. The blue and purple nodes represent the practical steps carried out in the laboratory such as the allocation to groups, the group sizes and role in the experiment, the treatments and the measurements taken. The green and red nodes represent the analysis, the outcome measures and the independent variables of interest and nuisance variables (e.g., blocking factors). For more details, see https://eda.nc3rs.org.uk.
See this image and copyright information in PMC

References

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    1. Kilkenny C, Browne WJ, Cuthill IC, Emerson M, Altman DG. PLoS Biol. 2010;8:e1000412. - PMC - PubMed
    1. Nosek BA, Ebersole CR, DeHaven AC, Mellor DT. 2017 doi: 10.17605/OSF.IO/2DXU5. Preprint at. - DOI
    1. Percie du Sert N, et al. PLoS Biol. 2017;15:e2003779. - PMC - PubMed

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