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. 2017 Nov-Dec;50(6):744-747.
doi: 10.1016/j.jelectrocard.2017.08.006. Epub 2017 Aug 8.

Benchmarking heart rate variability toolboxes

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Benchmarking heart rate variability toolboxes

Adriana N Vest et al. J Electrocardiol. 2017 Nov-Dec.

Abstract

Background: Heart rate variability (HRV) metrics hold promise as potential indicators for autonomic function, prediction of adverse cardiovascular outcomes, psychophysiological status, and general wellness. Although the investigation of HRV has been prevalent for several decades, the methods used for preprocessing, windowing, and choosing appropriate parameters lack consensus among academic and clinical investigators.

Methods: A comprehensive and open-source modular program is presented for calculating HRV implemented in Matlab with evidence-based algorithms and output formats. We compare our software with another widely used HRV toolbox written in C and available through PhysioNet.org.

Results: Our findings show substantially similar results when using high quality electrocardiograms (ECG) free from arrhythmias.

Conclusions: Our software shows equivalent performance alongside an established predecessor and includes validated tools for performing preprocessing, signal quality, and arrhythmia detection to help provide standardization and repeatability in the field, leading to fewer errors in the presence of noise or arrhythmias.

Keywords: Heart rate variability; Peak detection; Physiological signal processing; Toolbox benchmarking.

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References

    1. Malik M Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Heart rate variability. Standards of measurement, physiological interpretation, and clinical use. Circulation. 1996;93(5):1043–1065. - PubMed
    1. Clifford G. Signal processing methods for heart rate variability. University of Oxford; 2002.
    1. Pan Q, Zhou G, Wang R. Do the deceleration/acceleration capacities of heart rate reflect cardiac sympathetic or vagal activity? A model study. Medical and Biological Engineering and Computing. 2016;54(12):1921–1933. - PubMed
    1. Mietus JE, Goldberger AL. Heart Rate Variability Analysis with the HRV Toolkit - PhysioNet January, 23 2014 August 2016. Available from: https://physionet.org/tutorials/hrv-toolkit/
    1. Clifford GD. ECG Statistics, Noise, Artifacts, and Missing Data. In: Clifford GD, Azuaje F, McSharry P, editors. Advanced Methods And Tools for ECG Data Analysis. Artech House, Inc; 2006.

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