Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Nov;14(11):1079-1082.
doi: 10.1038/nmeth.4459. Epub 2017 Oct 2.

NeuBtracker-imaging neurobehavioral dynamics in freely behaving fish

Panagiotis Symvoulidis  1   2   3 , Antonella Lauri  1   2   3 , Anca Stefanoiu  4 , Michele Cappetta  1   2   3 , Steffen Schneider  3 , Hongbo Jia  5 , Anja Stelzl  1   2 , Maximilian Koch  1 , Carlos Cruz Perez  1   2 , Ahne Myklatun  1   2   3 , Sabine Renninger  6 , Andriy Chmyrov  1   7 , Tobias Lasser  4 , Wolfgang Wurst  2 , Vasilis Ntziachristos  1   7 , Gil G Westmeyer  1   2   3
Affiliations

NeuBtracker-imaging neurobehavioral dynamics in freely behaving fish

Panagiotis Symvoulidis et al. Nat Methods. 2017 Nov.

Abstract

A long-standing objective in neuroscience has been to image distributed neuronal activity in freely behaving animals. Here we introduce NeuBtracker, a tracking microscope for simultaneous imaging of neuronal activity and behavior of freely swimming fluorescent reporter fish. We showcase the value of NeuBtracker for screening neurostimulants with respect to their combined neuronal and behavioral effects and for determining spontaneous and stimulus-induced spatiotemporal patterns of neuronal activation during naturalistic behavior.

PubMed Disclaimer

Comment in

References

    1. Curr Biol. 2013 Feb 18;23(4):307-11 - PubMed
    1. Nat Methods. 2015 Nov;12(11):1039-46 - PubMed
    1. Nature. 2012 May 09;485(7399):471-7 - PubMed
    1. Dev Biol. 2015 Jan 1;397(1):1-17 - PubMed
    1. Front Behav Neurosci. 2016 Aug 19;10:160 - PubMed

LinkOut - more resources