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Case Reports
. 2017 Aug;11(8):OD10-OD11.
doi: 10.7860/JCDR/2017/28919.10433. Epub 2017 Aug 1.

Insulin Injection Site Adverse Effect in a Type 1 Diabetes Patient: An Unusual Presentation

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Case Reports

Insulin Injection Site Adverse Effect in a Type 1 Diabetes Patient: An Unusual Presentation

Ranjana Ajit Sahasrabudhe et al. J Clin Diagn Res. 2017 Aug.

Abstract

Insulin is an integral part of Type 1 diabetes management. Patient education is of utmost importance to ensure proper injection technique for getting appropriate glycaemic control as well as to avoid injection site adverse effects. Commonest injection site adverse effect is lipodystrophy, attributable to localized manifestation of the pharmacological action of insulin. However, we present a case where incorrect injection technique led to an unusual presentation of injection site adverse effect. Apart from the abnormal skin changes, the incorrect technique also adversely affected the glycaemic control. Though less prominent, some marks are still evident one and a half years after correction of the injection technique. However, the glycaemic control has substantially improved. This emphasizes the need of proper patient education regarding insulin injection technique.

Keywords: Insulin injection technique; Patient education; Site rotation; Skin pigmentation.

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Figures

[Table/Fig-1]:
[Table/Fig-1]:
Affected injection sites showing lipohypertrophy and injection scar marks of varying grades of pigmentation. a) Right arm; b) Left arm; c) Right thigh
[Table/Fig-2]:
[Table/Fig-2]:
Affected injection sites showing faded injection scar marks 1.5 years after correction of injection technique. a) Right arm; b) Left arm

References

    1. Khadilkar V, Yadav S, Agrawal KK, Tamboli S, Banerjee M, Cherian A, et al. Revised IAP growth charts for height, weight and body mass index for 5-18 year old Indian children. Indian Pediatrics. 2015;52:47–55. - PubMed
    1. Shrivastava SR, Shrivastava PS, Ramasamy J. Role of self-care in management of diabetes mellitus. Journal of Diabetes and Metabolic Disorders. 2013;12:14. - PMC - PubMed
    1. Tandon N, Kalra S, Balhara YPS, Baruah MP, Manoj Chadha M, Chandalia HB. Forum for Injection technique (FIT), India: The Indian recommendations 2.0, for best practice in insulin injection technique 2015. IJEM. 2015;19(3):317–31. - PMC - PubMed
    1. The Forum for Injection Technique - FIT odcTM International. Accessed on 8th March 2016 from http://www.fit4diabetes.com.
    1. TA Chowdhury, V Escudier. Poor glycaemic control caused by insulin lipohypertrophy. BMJ. 2003;327:383–84. - PMC - PubMed

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