Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2018 Mar 1;175(3):242-250.
doi: 10.1176/appi.ajp.2017.17010089. Epub 2017 Oct 3.

Improving the Efficiency of Psychotherapy for Depression: Computer-Assisted Versus Standard CBT

Affiliations
Randomized Controlled Trial

Improving the Efficiency of Psychotherapy for Depression: Computer-Assisted Versus Standard CBT

Michael E Thase et al. Am J Psychiatry. .

Abstract

Objective: The authors evaluated the efficacy and durability of a therapist-supported method for computer-assisted cognitive-behavioral therapy (CCBT) in comparison to standard cognitive-behavioral therapy (CBT).

Method: A total of 154 medication-free patients with major depressive disorder seeking treatment at two university clinics were randomly assigned to either 16 weeks of standard CBT (up to 20 sessions of 50 minutes each) or CCBT using the "Good Days Ahead" program. The amount of therapist time in CCBT was planned to be about one-third that in CBT. Outcomes were assessed by independent raters and self-report at baseline, at weeks 8 and 16, and at posttreatment months 3 and 6. The primary test of efficacy was noninferiority on the Hamilton Depression Rating Scale at week 16.

Results: Approximately 80% of the participants completed the 16-week protocol (79% in the CBT group and 82% in the CCBT group). CCBT met a priori criteria for noninferiority to conventional CBT at week 16. The groups did not differ significantly on any measure of psychopathology. Remission rates were similar for the two groups (intent-to-treat rates, 41.6% for the CBT group and 42.9% for the CCBT group). Both groups maintained improvements throughout the follow-up.

Conclusions: The study findings indicate that a method of CCBT that blends Internet-delivered skill-building modules with about 5 hours of therapeutic contact was noninferior to a conventional course of CBT that provided over 8 additional hours of therapist contact. Future studies should focus on dissemination and optimizing therapist support methods to maximize the public health significance of CCBT.

Keywords: Cognitive Therapy; Computer-Assisted Therapy; Mood Disorders-Depression; Psychotherapy.

PubMed Disclaimer

Conflict of interest statement

Disclosures

No of the other authors report disclosures or potential conflicts of interest.

Figures

Figure 1
Figure 1
Treatment Outcome: Mean Hamilton Rating Scale for Depression Scores

Comment in

Similar articles

Cited by

References

    1. American Psychiatric Association. Practice guideline for the treatment of patients with major depressive disorder. Third. Arlington, VA: Available at http://www.guideline.gov/content.aspx?id=24158. Accessed November 27, 2016. - PubMed
    1. Parikh SV, Quilty LC, Ravitz P, et al. Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder: Section 2. Psychological Treatments. Can J Psychiatry. 2016;61(9):524–539. - PMC - PubMed
    1. Cuijpers P, Berking M, Andersson G, Quigley L, Kleiboer A, Dobson KS. A meta-analysis of cognitive-behavioural therapy for adult depression, alone and in comparison with other treatments. Can J Psychiatry. 2013;58(7):376–385. - PubMed
    1. Cuijpers P, van Straten A, van Oppen P, Andersson G. Are psychological and pharmacologic interventions equally effective in the treatment of adult depressive disorders? A meta-analysis of comparative studies. J Clin Psychiatry. 2008;69(11):1675–1685. - PubMed
    1. Weitz ES, Hollon SD, Twisk J, et al. Baseline Depression Severity as Moderator of Depression Outcomes Between Cognitive Behavioral Therapy vs Pharmacotherapy: An Individual Patient Data Meta-analysis. JAMA Psychiatry. 2015;72(11):1102–1109. - PubMed

Publication types

LinkOut - more resources