Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 Sep;20(3):217-227.
doi: 10.4048/jbc.2017.20.3.217. Epub 2017 Sep 22.

Sentinel Lymph Node Biopsy in Breast Cancer: A Clinical Review and Update

Sheikh Zahoor  1 , Altaf Haji  1 , Azhar Battoo  1 , Mariya Qurieshi  2 , Wahid Mir  1 , Mudasir Shah  1
Affiliations
Review

Sentinel Lymph Node Biopsy in Breast Cancer: A Clinical Review and Update

Sheikh Zahoor et al. J Breast Cancer. 2017 Sep.

Abstract

Sentinel lymph node biopsy has become a standard staging tool in the surgical management of breast cancer. The positive impact of sentinel lymph node biopsy on postoperative negative outcomes in breast cancer patients, without compromising the oncological outcomes, is its major advantage. It has evolved over the last few decades and has proven its utility beyond early breast cancer. Its applicability and efficacy in patients with clinically positive axilla who have had a complete clinical response after neoadjuvant chemotherapy is being aggressively evaluated at present. This article discusses how sentinel lymph node biopsy has evolved and is becoming a useful tool in new clinical scenarios of breast cancer management.

Keywords: Breast neoplasms; Lymphatic metastasis; Neoadjuvant therapy; Sentinel lymph node biopsy.

PubMed Disclaimer

Conflict of interest statement

CONFLICT OF INTEREST: The authors declare that they have no competing interests.

References

    1. International Agency for Research on Cancer. Estimated number of incident cases, worldwide (top 10 cancer sites) in 2012. [Accessed August 12th, 2017]. http://gco.iarc.fr/today/online-analysis-pie?mode=cancer&mode_population....
    1. International Agency for Research on Cancer. Breast cancer: estimated incidence, mortality and prevalence worldwide in 2012. [Accessed August 12th, 2017]. http://globocan.iarc.fr/Pages/fact_sheets_cancer.aspx.
    1. National Cancer Institute: Surveillance, Epidemiology and End Results Program. Cancer stat facts: female breast cancer. [Accessed August 12th, 2017]. https://seer.cancer.gov/statfacts/html/breast.html.
    1. Halsted WS. I. The results of radical operations for the cure of carcinoma of the breast. Ann Surg. 1907;46:1–19. - PMC - PubMed
    1. Sleeman J, Schmid A, Thiele W. Tumor lymphatics. Semin Cancer Biol. 2009;19:285–297. - PubMed

LinkOut - more resources