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Randomized Controlled Trial
. 2017 Oct 3;18(1):452.
doi: 10.1186/s13063-017-2190-2.

Effectiveness of two web-based cognitive bias modification interventions targeting approach and attentional bias in gambling problems: study protocol for a pilot randomised controlled trial

Marilisa Boffo  1   2   3 , Ronny Willemen  4   5 , Thomas Pronk  6 , Reinout W Wiers  6 , Geert Dom  4
Affiliations
Randomized Controlled Trial

Effectiveness of two web-based cognitive bias modification interventions targeting approach and attentional bias in gambling problems: study protocol for a pilot randomised controlled trial

Marilisa Boffo et al. Trials. .

Abstract

Background: Disordered gamblers have phenotypical and pathological similarities to those with substance use disorders (SUD), including exaggerated automatic cognitive processing of motivationally salient gambling cues in the environment (i.e., attentional and approach bias). Cognitive bias modification (CBM) is a family of computerised interventions that have proved effective in successfully re-training these automatic cognitive biases in SUD. CBM interventions can, in principle, be administered online, thus showing potential of being a low-cost, low-threshold addition to conventional treatments. This paper presents the design of a pilot randomised controlled trial exploring the effectiveness of two web-based CBM interventions targeting attentional and approach bias towards gambling cues in a sample of Dutch and Belgian problematic and pathological gamblers.

Methods/design: Participants (N = 182) are community-recruited adults experiencing gambling problems, who have gambled at least twice in the past 6 months and are motivated to change their gambling behaviour. After a baseline assessment session, participants are randomly assigned to one of four experimental conditions (attentional or approach bias training, or the placebo version of the two trainings) and complete six sessions of training. At baseline and before each training session, participants receive automated personalised feedback on their gambling motives and reasons to quit or reduce gambling. The post-intervention, 1-month, and 3-month follow-up assessments will examine changes in gambling behaviour, with frequency and expenditure as primary outcomes, and depressive symptoms and gambling-related attentional and approach biases as secondary outcomes. Secondary analyses will explore possible moderators (interference control capacity and trait impulsivity) and mediators (change in cognitive bias) of training effects on the primary outcomes.

Discussion: This study is the first to explore the effectiveness of an online CBM intervention for gambling problems. The results of this study can be extremely valuable for developing e-health interventions for gambling problems and further understanding the role of motivational implicit cognitive processes underlying problematic gambling behaviour.

Trial registration: Netherlands Trial Register, NTR5096 . Registered on 11 March 2015.

Keywords: Addiction; Approach bias; Attentional bias; Cognitive bias modification; Gambling; Randomised controlled trial; e-health.

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Conflict of interest statement

Ethics approval and consent to participate

The study protocol (version 1.3 dated 15-07-2014) has been approved by the Medical Ethics Committee of the University of Antwerp (October 2014, Belgian registration number: B300201422158) and by the Ethics Committee of the University of Amsterdam (August 2014, Protocol number: 2014-DP-3774). Upon registration on the study online platform, participants must read the information page and provide digital informed consent in order to participate in the study.

Consent for publication

The results of this study will be presented to the public and the scientific community through publications in scientific journals and presentations at conferences. Participants are fully informed that the results of the study will be published in anonymised format and are further asked to give their permission to do so in the digital informed consent form.

Competing interests

The authors declare that they have no competing interests.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Figures

Fig. 1
Fig. 1
CONSORT flow diagram of participants' progress through the phases of the RCT
Fig. 2
Fig. 2
SPIRIT Figure: Schedule of forms and procedures per study time point
See this image and copyright information in PMC

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