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Comment
. 2017 Oct;7(10):1062-1064.
doi: 10.1158/2159-8290.CD-17-0858.

More T Cells versus Better T Cells in Patients with Breast Cancer

Daniel E Speiser  1 , Grégory Verdeil  2
Affiliations
Comment

More T Cells versus Better T Cells in Patients with Breast Cancer

Daniel E Speiser et al. Cancer Discov. 2017 Oct.

Abstract

<b/> Characterization of intratumoral leukocyte populations may help in estimating patients' prognosis and predictions. A new study shows remarkable differences between the in situ and invasive breast cancer stages and highlights that cell number analyses should be complemented with characterization of T-cell functions, increasing the likelihood that immune competent antitumor T cells and further biomarkers are identified for guiding therapy choices. Cancer Discov; 7(10); 1062-4. ©2017 AACR.See related article by Gil Del Alcazar et al., p. 1098.

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  • Immune Escape in Breast Cancer During In Situ to Invasive Carcinoma Transition.
    Gil Del Alcazar CR, Huh SJ, Ekram MB, Trinh A, Liu LL, Beca F, Zi X, Kwak M, Bergholtz H, Su Y, Ding L, Russnes HG, Richardson AL, Babski K, Min Hui Kim E, McDonnell CH 3rd, Wagner J, Rowberry R, Freeman GJ, Dillon D, Sorlie T, Coussens LM, Garber JE, Fan R, Bobolis K, Allred DC, Jeong J, Park SY, Michor F, Polyak K. Gil Del Alcazar CR, et al. Cancer Discov. 2017 Oct;7(10):1098-1115. doi: 10.1158/2159-8290.CD-17-0222. Epub 2017 Jun 26. Cancer Discov. 2017. PMID: 28652380 Free PMC article.

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