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Case Reports
. 2017 Sep 19:7:480.
doi: 10.7916/D8V416KN. eCollection 2017.

Development of Hyperkinesias after Long-term Pallidal Stimulation for Idiopathic Segmental Dystonia

Andreas Wloch  1 , Christian Blahak  2 , Mahmoud Abdallat  1 , Hans E Heissler  1 , Marc E Wolf  2 , Joachim K Krauss  1
Affiliations
Case Reports

Development of Hyperkinesias after Long-term Pallidal Stimulation for Idiopathic Segmental Dystonia

Andreas Wloch et al. Tremor Other Hyperkinet Mov (N Y). .

Abstract

Background: Chronic deep brain stimulation (DBS) of the globus pallidus internus (GPi) has become an established treatment for dystonia. While bradykinetic symptoms may occur on chronic stimulation, the appearance of hyperkinetic movements has not been well characterized.

Case report: We report on the development of hyperkinesias after more than 10 years of GPi DBS.

Discussion: Hyperkinesias may evolve upon long-term GPi DBS in dystonia. This might be related to a combined effect consisting of a reduced threshold for effective GPi stimulation for dystonia and spread of current to the globus pallidus externus.

Keywords: Deep brain stimulation; dystonia; globus pallidus; hyperkinesias; long term.

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Conflict of interest statement

Funding: None. Conflicts of Interest: The authors report no conflict of interest. Ethics Statement: All patients that appear on video have provided written informed consent; authorization for the videotaping and for publication of the videotape was provided.

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