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Review
. 2017 Jul-Sep;6(3):93-98.
doi: 10.4103/sajc.sajc_96_17.

Human papillomavirus in head and neck cancer in India: Current status and consensus recommendations

Affiliations
Review

Human papillomavirus in head and neck cancer in India: Current status and consensus recommendations

Vedang Murthy et al. South Asian J Cancer. 2017 Jul-Sep.

Abstract

Human papillomavirus (HPV) associated head and neck squamous cell cancers (HNSCC) have become increasingly common in the West, but the same cannot be said about India. These cancers have a different biology and confer a better prognosis, however, its current role in the management of patients in India is not clearly defined. At the 35th Indian Cooperative Oncology Network conference held in September 2016, a panel of radiation, surgical and medical oncologists, pathologists, and basic scientists from across the country having experience in clinical research with respect to HPV in HNSCC reviewed the available literature from India. All the ideas and facts were thereafter collated in this report. Various topics of controversy in dealing with the diagnosis and management of HPV-associated HNSCC have been highlighted in this report in context to the Indian scenario. Furthermore, the prevalence of the same and its association with tobacco and high-risk sexual behavior has been touched on. Conclusively, a set of recommendations has been proposed by the panel to guide the practicing oncologists of the country while dealing with HPV-associated HNSCC.

Keywords: Consensus recommendations; India; head and neck squamous cell cancers; human papillomavirus.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
p16 IHC showing >70% staining

References

    1. Chaturvedi AK, Engels EA, Pfeiffer RM, Hernandez BY, Xiao W, Kim E, et al. Human papillomavirus and rising oropharyngeal cancer incidence in the United States. J Clin Oncol. 2011;29:4294–301. - PMC - PubMed
    1. Sturgis EM, Cinciripini PM. Trends in head and neck cancer incidence in relation to smoking prevalence: An emerging epidemic of human papillomavirus-associated cancers? Cancer. 2007;110:1429–35. - PubMed
    1. Datta S, Chaturvedi P, Mishra A, Pawar P. A review of Indian literature for association of smokeless tobacco with malignant and premalignant diseases of head and neck region. Indian J Cancer. 2014;51:200–8. - PubMed
    1. International Institute for Population Sciences. Ministry of Health and Family Welfare. Government of India, Global Adult Tobacco Survey India 2009-2010. 2010
    1. Centers for Disease Control and Prevention (CDC). Cigarette smoking among adults – United States, 2006. MMWR Morb Mortal Wkly Rep. 2007;56:1157–61. - PubMed