Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Dec;32(12):1789-1790.
doi: 10.1002/mds.27176. Epub 2017 Oct 4.

The Cats-and-Dogs test: A tool to identify visuoperceptual deficits in Parkinson's disease

Affiliations

The Cats-and-Dogs test: A tool to identify visuoperceptual deficits in Parkinson's disease

Rimona S Weil et al. Mov Disord. 2017 Dec.
No abstract available

Keywords: Parkinson's disease; biomarker; cognition; dementia; vision.

PubMed Disclaimer

Figures

Figure 1
Figure 1
(A) Left: Cats‐and‐Dogs test, example skewed image. A dog is shown. Images in this task varied in the amount of skew, and performance at each level of skew was recorded. Right: control task, example image with added visual noise. A cat is shown. Images in this task varied in the amount of visual noise, and performance at each level of noise was recorded. (B) Method for determining performance in the Cats‐and‐Dogs test; psychophysical curves for 2 example participants are shown, one with PD (black), one without (gray). Percentage correct is shown for each level of skew. Performance is defined as the skew level corresponding to 75% (midway between perfect 100% and guess at 50%) and is marked for each of the participants. The same method was used to determine performance in the control task, with amount of noise plotted against percentage correct. (arbitrary units [a.u.]). (C) Left: performance in the Cats‐and‐Dogs test in patients with Parkinson's disease and controls. Patients with Parkinson's disease performed worse than healthy controls, with lower thresholds to correctly identify skewed images. Wider variation in performance was also seen in patients with Parkinson's disease. Right: performance in the control test in patients with Parkinson's disease and controls. There was no significant difference in performance in this task between patients with Parkinson's disease and healthy controls. (a.u.). (D) Relationship between performance in the Cats‐and‐Dogs test and overall cognition (Montreal Cognitive Assessment).

References

    1. Williams‐Gray CH, Mason SL, Evans JR, et al. The CamPaIGN study of Parkinson's disease: 10‐year outlook in an incident population‐based cohort. J Neurol Neurosurg Psychiatry 2013;84(11):1258‐1264. - PubMed
    1. Bohnen NI, Koeppe RA, Minoshima S, et al. Cerebral glucose metabolic features of Parkinson disease and incident dementia: longitudinal study. J Nucl Med 2011;52(6):848‐855. - PMC - PubMed
    1. Toledo JB, Gopal P, Raible K, et al. Pathological alpha‐synuclein distribution in subjects with coincident Alzheimer's and Lewy body pathology. Acta Neuropathol 2016;131(3):393‐409. - PMC - PubMed
    1. Hipp G, Diederich NJ, Pieria V, Vaillant M. Primary vision and facial emotion recognition in early Parkinson's disease. J Neurol Sci 2014;338(1‐2):178‐182. - PubMed
    1. von AL, Maurer B, McMillen C, Abraham D, Blum M. reCAPTCHA: human‐based character recognition via Web security measures. Science 2008;321(5895):1465‐1468. - PubMed

Publication types