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Case Reports
. 2017 Oct 5;11(1):284.
doi: 10.1186/s13256-017-1426-9.

Pseudoangiomatous stromal hyperplasia - a benign and rare tumor of the breast in an adolescent: a case report

Alberto Testori  1 , Marco Alloisio  2 , Valentina Errico  2 , Edoardo Bottoni  2 , Emanuele Voulaz  2 , Bethania Fernandez  3 , Stefano Meroni  4 , Matilde De Simone  5 , Ugo Cioffi  5
Affiliations
Case Reports

Pseudoangiomatous stromal hyperplasia - a benign and rare tumor of the breast in an adolescent: a case report

Alberto Testori et al. J Med Case Rep. .

Abstract

Background: Pseudoangiomatous stromal hyperplasia is an uncommon mesenchymal breast neoplasm.

Case presentation: Here we present a case of an 11-year old hispanic girl affected by bilateral mammary nodular pseudoangiomatous stromal hyperplasia, an uncommon breast disease, with a review of the literature related to diagnostic workup, differential diagnosis, and management. A rapidly growing mass in the breast may be stressful for both parents and child as the suspicion of malignancy arises. Multiple wide excisions of both breasts were performed.

Conclusions: The purpose of this case report is to draw attention to the fact that most emerging lesions of the breast in girls during puberty are benign diseases.

Keywords: Benign breast disease; Mesenchymal breast neoplasm; Pseudoangiomatous stromal hyperplasia (PASH).

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Conflict of interest statement

Ethics approval and consent to participate

Not applicable.

Consent for publication

Written informed consent was obtained from the patient’s legal guardian(s) for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.

Competing interests

The authors declare that they have no competing interests, including specific financial interests or relationships and affiliations relevant to the subject matter or materials discussed in the manuscript.

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Figures

Fig. 1
Fig. 1
Preoperative view of the patient showing asymmetrically enlarged breasts
Fig. 2
Fig. 2
Postoperative view after bilateral multiple wide excision
Fig. 3
Fig. 3
The gross image of the right (a) and left (b) mammary masses shows well-demarcated, rubbery-firm, tan-brown external surfaces
Fig. 4
Fig. 4
The fibroadenoma (×10) at histology
Fig. 5
Fig. 5
Some focal aspects of pseudoangiomatous stromal hyperplasia (× 20) at histology made of complex interconnected slit-like channels lined by spindle cells in collagenous stroma
See this image and copyright information in PMC

References

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