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Review
. 2017 Sep;49(3):182-191.

Cerebral Oximetry and Autoregulation during Cardiopulmonary Bypass: A Review

Nousjka P A Vranken  1 , Patrick W Weerwind  1 , Nadia A Sutedja  2 , Ervin E Ševerdija  1 , Paul J C Barenbrug  1 , Jos G Maessen  1
Affiliations
Review

Cerebral Oximetry and Autoregulation during Cardiopulmonary Bypass: A Review

Nousjka P A Vranken et al. J Extra Corpor Technol. 2017 Sep.

Abstract

Postoperative neurological complications (PNCs) following cardiac surgery with cardiopulmonary bypass (CPB) is a detrimental complication, contributing to increased mortality rates and health care costs. To prevent intraoperative cerebral desaturations associated with PNC, continuous brain monitoring using near-infrared spectroscopy has been advocated. However, clear evidence for a defined desaturation threshold requiring intervention during CPB is still lacking. Since cerebral oximetry readings are nonspecific, cerebral tissue oxygenation values need to be interpreted with caution and in the context of all available clinical information. Therefore, maintaining an intact autoregulatory activity during CPB rather than solely focusing on regional cerebral oxygen saturation measurements will collectively contribute to optimization of patient care during CPB.

Keywords: cardiopulmonary bypass; cerebral autoregulation; cerebral oximetry; postoperative neurological complications.

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