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. 2017 Sep 27;3(9):925-926.
doi: 10.1021/acscentsci.7b00396. Epub 2017 Sep 13.

Toward Understanding "the Ways" of Allosteric Drugs

Rommie E Amaro  1
Affiliations

Toward Understanding "the Ways" of Allosteric Drugs

Rommie E Amaro. ACS Cent Sci. .
No abstract available

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Figures

Figure 1
Figure 1
Allosteric drugs work by manipulating binding pockets away from active sites to effect global conformational changes, making them harder to predict.
See this image and copyright information in PMC

References

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