EVALUATION OF RADIATION ABSORBED DOSE AND IMAGE QUALITY IN DIFFERENT RETROSPECTIVE-ECG GATING ACQUISITION METHODS OF CARDIAC CT ANGIOGRAPHY

Abstract

Cardiac computed tomography angiography (CCTA) studies have risen concern of radiobiological effects over the patients. Therefore, estimating radiation doses absorbed during CCTA is important. In this study, we compared radiation dose and image quality by using three different retrospective electrocardiography (ECG) protocols. A total of 123 patients undergoing CCTA were divided in three different groups. We used full-dose modulation (CareDose4D) technique in group (1); fixed tube current 200 mAs for group (2); and in group (3), chest circumference was used to adapt tube current (180-200 mAs) and tube potential (100-120 kVp). For groups (1) and (2), tube potential adapted depends on body mass index (BMI) in which it was 100 kVp for BMI < 27 kg/m2, and 120 kVp for BMI ≥ 27 kg/m2. Quantitive assessment of image quality was calculated by measuring signal intensity (SI) and image noise (IN) in the proximal segments of aorta root on left and right coronary arteries. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were also calculated by using SI and IN. Two experienced radiologists using a 4-point scale assessed the subjective image quality. Our results show that in group (1), the mean effective dose was 4.46 mSv (range: 1.75-8.6 mSv) and for group (2), the mean effective radiation dose was 5.07 mSv (range: 2.57-9.74 mSv) and in group (3), the mean effective dose was 5.85 mSv (range: 3.36-12.17 mSv). Group (1) representing 12% and 23% decrease in radiation dose comparing by groups (2) and (3). In multivariate analysis, adjusting for BMI, radiation dose for patients with BMI < 27 kg/m2 was significantly different; 2.53 mSv for group (1) compared to 3.54 mSv in group (2) and 5.207 in group (3) (p < 0.0001). In addition, lowering tube potential from 120 to 100 kVp in 200 mAs fixed tube current, represents 27% decrease in radiation dose. The quantitative image quality (IN, SI, SNR and CNR) was not statistically significant among the groups. To sum up, Retrospective-ECG gating may reduce radiation dose by using automatic tube current modulation and 100kVp tube potential with preservation of image quality in patient's whose BMI < 27 kg/m2.