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Case Reports
. 2015 Oct;6(5):456-458.
doi: 10.14740/wjon945w. Epub 2015 Oct 26.

Diffuse Gastric Cancer During Pregnancy: Report of a Rare Association

Orivaldo Alves Barbosa  1 , Anna Dorotheia Bezerra de Souza  2 , Mayna Raphaela de Carvalho Moura  2 , Elson Jose de Almeida Junior  2 , Joao Paulo Uchoa Fontenele  3 , Fabio de Figuereido Chaves  4 , Jose Walter Correia  1
Affiliations
Case Reports

Diffuse Gastric Cancer During Pregnancy: Report of a Rare Association

Orivaldo Alves Barbosa et al. World J Oncol. 2015 Oct.

Abstract

Gastric cancer during pregnancy is a rare event and difficult to diagnose, as the symptoms can be confused with those of an ordinary pregnancy. We report a case of a 25-year-old patient with a 29-week gestation, with asthenia complaint, vomiting and weight loss. During the investigation of wasting syndrome endoscopy was performed with infiltrative ulcerative lesions in pre-pyloric region with biopsy revealing carcinoma with signet ring, undifferentiated type. It was held on a strict control of fetal vitality, and pregnancy was interrupted via the abdominal delivery at 34 weeks. Soon after the cesarean section was performed, exploratory laparotomy was performed to perform inventory of the abdominal cavity, being observed the presence of carcinomatous implants in the peritoneum. In the face of irresectability clinical conduct was adopted and the patient was sent to chemotherapy, ensuring nutrition via a jejunostomy. The article reviews the gastric carcinoma association with pregnancy, discussing the initiation of treatment and continuity of pregnancy.

Keywords: Gastric cancer; Peritoneal metastases; Pregnancy; Prematurity; Prognosis.

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Figures

Figure 1
Figure 1
Multiple small cells infiltrating the lamina propria of the gastric mucosa, H&E, × 100 (arrow).
Figure 2
Figure 2
Detail of signet ring cell with mucinous cytoplasm and core diverted to the cell periphery, H&E, × 400 (arrow).
Figure 3
Figure 3
Abdominal tomography with intravenous contrast revealing intense thickening of the gastric wall with diffuse narrowing in the pre-pyloric region (asterisk).
See this image and copyright information in PMC

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