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. 2016 Dec;7(5-6):109-118.
doi: 10.14740/wjon980w. Epub 2016 Dec 23.

Incidence and Mortality of Nasopharynx Cancer and Its Relationship With Human Development Index in the World in 2012

Neda Mahdavifar  1 , Farhad Towhidi  2 , Behnam Reza Makhsosi  2 , Reza Pakzad  3 , Ali Moini  4 , Abbas Ahmadi  2 , Sarah Lotfi  2 , Hamid Salehiniya  5   6
Affiliations

Incidence and Mortality of Nasopharynx Cancer and Its Relationship With Human Development Index in the World in 2012

Neda Mahdavifar et al. World J Oncol. 2016 Dec.

Abstract

Background: One of the most common cancers in head and neck is nasopharynx. Knowledge about the incidence and mortality of this disease and its distribution in terms of geographical areas is necessary for further study, better planning and prevention. Therefore, this study aimed to determine the incidence and mortality of nasopharynx cancer and its relationship with human development index (HDI) in the world in 2012.

Methods: This study was an ecological study conducted based on GLOBOCAN project of World Health Organization (WHO) for the countries in world. The correlation between standardized incidence rates (SIRs) and standardized mortality rates (SMRs) of nasopharynx cancer with HDI and its components was assessed with correlation coefficient by using SPSS 15.

Results: In 2012, 86,691 nasopharynx cancer cases occurred in the world, so that 60,896 new cases were seen in men and 25,795 new cases in women (sex ratio = 2.36). SIR of the cancer was 1.2 per 100,000 (1.7 in men and 0.7 in women per 100,000) in the world. In 2012, 50,831 nasopharynx death cases occurred in the world, so that 35,756 death cases were seen in men and 15,075 death cases in women (sex ratio = 2.37). SIR of mortality from the cancer was 0.7 per 100,000 (0.7 in women and 1 in men per 100,000) in the world. The results of correlation analysis showed a negative correlation between the SIR and HDI (r = -0.037, P = 0.629), and also the results of correlation analysis showed a negative correlation between the SMR and HDI (r = -0.237, P = 0.002).

Conclusion: Nasopharyngeal cancer is native to Southeast Asia and the highest incidence and mortality were seen in countries with moderate and low HDI. It is suggested that studies are conducted on determining the causes of the cancer incidence and mortality in the world and the differences between various regions.

Keywords: Human development index; Incidence; Mortality; Nasopharynx cancer; World.

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Conflict of interest statement

None.

Figures

Figure 1
Figure 1
Distribution of standardized nasopharynx cancer incidence rate in the world (extracted from GLOBOCAN, 2012).
Figure 2
Figure 2
Distribution of standardized nasopharynx cancer mortality rate in the world (extracted from GLOBOCAN, 2012).
Figure 3
Figure 3
Standardized incidence and mortality of nasopharynx cancer in different parts of the UN (extracted from GLOBOCAN, 2012).
Figure 4
Figure 4
The relationship between the standardized incidence rate and the human development index.
Figure 5
Figure 5
Relationship between standardized mortality rate and the human development index.
See this image and copyright information in PMC

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