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Comment
. 2017 Dec;13(12):706-707.
doi: 10.1038/nrneurol.2017.145. Epub 2017 Oct 6.

Alzheimer disease: ApoE4 implicated in tau-mediated neurodegeneration

Comment

Alzheimer disease: ApoE4 implicated in tau-mediated neurodegeneration

Heather Wood. Nat Rev Neurol. 2017 Dec.
No abstract available

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Comment on

  • ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.
    Shi Y, Yamada K, Liddelow SA, Smith ST, Zhao L, Luo W, Tsai RM, Spina S, Grinberg LT, Rojas JC, Gallardo G, Wang K, Roh J, Robinson G, Finn MB, Jiang H, Sullivan PM, Baufeld C, Wood MW, Sutphen C, McCue L, Xiong C, Del-Aguila JL, Morris JC, Cruchaga C; Alzheimer’s Disease Neuroimaging Initiative; Fagan AM, Miller BL, Boxer AL, Seeley WW, Butovsky O, Barres BA, Paul SM, Holtzman DM. Shi Y, et al. Nature. 2017 Sep 28;549(7673):523-527. doi: 10.1038/nature24016. Epub 2017 Sep 20. Nature. 2017. PMID: 28959956 Free PMC article.

References

    1. Nature. 2017 Sep 28;549(7673):523-527 - PubMed

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