Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 Nov 1;46(6):882-888.
doi: 10.1093/ageing/afx150.

New horizons in multimorbidity in older adults

Affiliations
Review

New horizons in multimorbidity in older adults

Alison J Yarnall et al. Age Ageing. .

Abstract

The concept of multimorbidity has attracted growing interest over recent years, and more latterly with the publication of specific guidelines on multimorbidity by the National Institute for Health and Care Excellence (NICE). Increasingly it is recognised that this is of particular relevance to practitioners caring for older adults, where multimorbidity may be more complex due to the overlap of physical and mental health disorders, frailty and polypharmacy. The overlap of frailty and multimorbidity in particular is likely to be due to the widespread health deficit accumulation, leading in some cases to functional impairment. The NICE guidelines identify 'target groups' who may benefit from a tailored approach to care that takes their multimorbidity into account, and make a number of research recommendations. Management includes a proactive individualised assessment and care plan, which improves quality of life by reducing treatment burden, adverse events, and unplanned or uncoordinated care.

Keywords: frailty; long-term conditions; multimorbidity; older people.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Diagram to indicate the need for an approach to care that takes account of multimorbidity [10]. Reproduced with permission National Guideline Centre (2016) Multimorbidity: clinical assessment and management (NG56). Published by the National Guidelines Centre at The Royal College of Physicians, 11 St Andrews Place, Regent's Park, London NW1 4LE. Copyright © NGC. Reproduced by permission.
Figure 2.
Figure 2.
Flowchart of the evolution of a single disease process to multimorbidity, functional impairment and finally frailty.

References

    1. Barnett K, Mercer SW, Norbury M, Watt G, Wyke S, Guthrie B. Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study. Lancet 2012; 380: 37–43. - PubMed
    1. Marengoni A, Angleman S, Melis R, Mangialasche F, Karp A, Garmen A et al. . Aging with multimorbidity: a systematic review of the literature. Ageing Res Rev 2011; 10: 430–9. - PubMed
    1. Marengoni A, von Strauss E, Rizzuto D, Winblad B, Fratiglioni L. The impact of chronic multimorbidity and disability on functional decline and survival in elderly persons. A community-based, longitudinal study. J Intern Med 2009; 265: 288–95. - PubMed
    1. Fortin M, Bravo G, Hudon C, Lapointe L, Almirall J, Dubois MF et al. . Relationship between multimorbidity and health-related quality of life of patients in primary care. Qual Life Res 2006. Feb; 15: 83–91. - PubMed
    1. Tyack Z, Frakes KA, Barnett A, Cornwell P, Kuys S, McPhail S. Predictors of health-related quality of life in people with a complex chronic disease including multimorbidity: a longitudinal cohort study. Qual Life Res 2016; 25: 2579–92. - PubMed

Publication types

MeSH terms