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Comment
. 2017 Oct 5;21(4):413-414.
doi: 10.1016/j.stem.2017.09.009.

The LUNGe to Model Alveolar Lung Diseases in a Dish

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The LUNGe to Model Alveolar Lung Diseases in a Dish

Zheng Wang et al. Cell Stem Cell. .
Free article

Abstract

Obtaining alveolar epithelial type 2 cells (AEC2s) from human pluripotent stem cells (hPSCs) offers great scientific and clinical promise. In this issue of Cell Stem Cell, Jacob et al. (2017) report a method for the directed differentiation of hPSCs into mature AEC2s and demonstrate its application in modeling alveolar lung diseases.

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  • Differentiation of Human Pluripotent Stem Cells into Functional Lung Alveolar Epithelial Cells.
    Jacob A, Morley M, Hawkins F, McCauley KB, Jean JC, Heins H, Na CL, Weaver TE, Vedaie M, Hurley K, Hinds A, Russo SJ, Kook S, Zacharias W, Ochs M, Traber K, Quinton LJ, Crane A, Davis BR, White FV, Wambach J, Whitsett JA, Cole FS, Morrisey EE, Guttentag SH, Beers MF, Kotton DN. Jacob A, et al. Cell Stem Cell. 2017 Oct 5;21(4):472-488.e10. doi: 10.1016/j.stem.2017.08.014. Epub 2017 Sep 28. Cell Stem Cell. 2017. PMID: 28965766 Free PMC article.

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