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. 1988 Jul 9;2(8602):70-2.
doi: 10.1016/s0140-6736(88)90005-0.

Alpha-interferon therapy for essential thrombocythaemia

F J Giles  1 , C R Singer, A G Gray, K L Yong, M Brozovic, S C Davies, I R Grant, A V Hoffbrand, S J Machin, A B Mehta, et al.
Affiliations

Alpha-interferon therapy for essential thrombocythaemia

F J Giles et al. Lancet. .

Abstract

18 patients with symptomatic essential thrombocythaemia were treated with recombinant alpha interferon (2a or 2b). Subcutaneous dosage regimens, which were well-tolerated, selectively lowered the platelet count and relieved symptoms in all patients, whether previously treated or untreated. Recombinant alpha-interferon may offer a non-leukaemogenic alternative therapy for these patients.

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