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Comparative Study
. 1988 Jul;85(13):4760-4.
doi: 10.1073/pnas.85.13.4760.

Hox-5.1 defines a homeobox-containing gene locus on mouse chromosome 2

M S Featherstone  1 , A Baron, S J Gaunt, M G Mattei, D Duboule
Affiliations
Comparative Study

Hox-5.1 defines a homeobox-containing gene locus on mouse chromosome 2

M S Featherstone et al. Proc Natl Acad Sci U S A. 1988 Jul.

Abstract

We have isolated a murine homeobox-containing gene, Hox-5.1, by virtue of its relatedness to the Hox-1.4 gene. In situ hybridization to metaphase spreads mapped Hox-5.1 to band D of mouse chromosome 2. Sequence comparisons indicate that Hox-5.1 is the murine homolog of the human C13 homeobox-containing gene. Hox-5.1 also bears significant similarity to the Xenopus Xhox-1A homeobox-containing gene and the Drosophila deformed homeotic gene at N-terminal and homeobox regions. Hox-5.1 transcripts were detected in mouse embryos, in adult mouse testis, kidney, heart, and intestine, and in mouse embryonal carcinoma cells treated with retinoic acid. In situ hybridization to sections from whole mouse embryos revealed Hox-5.1 expression in spinal cord and prevertebrae.

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References

    1. Proc Natl Acad Sci U S A. 1986 Dec;83(24):9532-6 - PubMed
    1. Z Anat Entwicklungsgesch. 1974;145(1):75-80 - PubMed
    1. EMBO J. 1986 Sep;5(9):2209-15 - PubMed
    1. Cell. 1985 Nov;43(1):19-28 - PubMed
    1. Nature. 1984 Jul 5-11;310(5972):25-31 - PubMed

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