Prevalence of glucose-6-phosphate dehydrogenase deficiency in neonates in Egypt
- PMID: 28988250
- PMCID: PMC6074198
- DOI: 10.5144/0256-4947.2017.362
Prevalence of glucose-6-phosphate dehydrogenase deficiency in neonates in Egypt
Abstract
Background: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked disorder which causes neonatal jaundice in most cases, and under certain conditions, can cause a spectrum of hemolytic manifestations.
Objective: To determine the local prevalence of G6PD deficiency in newborns.
Design: Cross-sectional.
Setting: University hospital.
Methods: Infants born during 2015 were prospectively screened for G6PD deficiency. Dried blood spot samples on filter paper were collected in collaboration with the central laboratories of the Ministry of Health. Quantitative measurement of G6PD enzyme activity was measured from the blood samples using fluorometric analysis. A value.
Conflict of interest statement
No conflict of interest to be declared.
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