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Review
. 2017 Nov 1;25(21):5891-5903.
doi: 10.1016/j.bmc.2017.09.035. Epub 2017 Sep 23.

Recently reported biological activities of pyrazole compounds

Jéssica Venância Faria  1 , Percilene Fazolin Vegi  2 , Ana Gabriella Carvalho Miguita  3 , Maurício Silva Dos Santos  4 , Nubia Boechat  5 , Alice Maria Rolim Bernardino  2
Affiliations
Review

Recently reported biological activities of pyrazole compounds

Jéssica Venância Faria et al. Bioorg Med Chem. .

Abstract

The pyrazole nucleus is an aromatic azole heterocycle with two adjacent nitrogen atoms. Pyrazole derivatives have exhibited a broad spectrum of biological activities, and approved pyrazole-containing drugs include celecoxib, antipyrine, phenylbutazone, rimonabant, and dipyrone. Many research groups have synthesized and evaluated pyrazoles against several biological agents. This review examines recent publications relating the structures of pyrazoles with their corresponding biological activities.

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