Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 Jun 23;2(3):172-175.
doi: 10.1136/svn-2017-000071. eCollection 2017 Sep.

Red blood cell distribution width and ischaemic stroke

Gang-Hua Feng  1 , Hai-Peng Li  1 , Qiu-Li Li  1 , Ying Fu  2 , Ren-Bin Huang  1
Affiliations
Review

Red blood cell distribution width and ischaemic stroke

Gang-Hua Feng et al. Stroke Vasc Neurol. .

Abstract

The red blood cell distribution width (RDW) is a measure of red blood cell (RBC) size heterogeneity, which is easily calculated by dividing the SD of erythrocyte volumes for the mean corpuscular volume. Recent reporter suggested that, besides haematological diseases and anaemia, many human disorders may be closely associated with the elevated RDW. A literature review has revealed the RDW may be closely related to the development of ischaemic stroke, carotid artery atherosclerosis and cerebral embolism. Higher RDW could independently predict adverse outcomes in patients in these conditions.

Keywords: Red blood cell distribution width (RDW); carotid artery atherosclerosis (CAS); cerebral embolism; ischaemic stroke.

PubMed Disclaimer

Conflict of interest statement

Competing interests: None declared.

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Lippi G, Plebani M. Red blood cell distribution width (RDW) and human pathology. One size fits all. Clin Chem Lab Med 2014;52:1247–9. doi:10.1515/cclm-2014-0585 - DOI - PubMed
    1. Salvagno GL, Sanchis-Gomar F, Picanza A, et al. . Red blood cell distribution width: a simple parameter with multiple clinical applications. Crit Rev Clin Lab Sci 2015;52:86–105. doi:10.3109/10408363.2014.992064 - DOI - PubMed
    1. Sousa R, Gonçalves C, Guerra IC, et al. . Increased red cell distribution width in fanconi Anemia: a novel marker of stress erythropoiesis. Orphanet J Rare Dis 2016;11:102 doi:10.1186/s13023-016-0485-0 - DOI - PMC - PubMed
    1. Förhécz Z, Gombos T, Borgulya G, et al. . Red cell distribution width in heart failure: prediction of clinical events and relationship with markers of ineffective erythropoiesis, inflammation, renal function, and nutritional state. Am Heart J 2009;158:659–66. doi:10.1016/j.ahj.2009.07.024 - DOI - PubMed
    1. Akkermans MD, Vreugdenhil M, Hendriks DM, et al. . Iron Deficiency in inflammatory bowel disease. J Pediatr Gastroenterol Nutr 2016:1 doi:10.1097/MPG.0000000000001406 - DOI - PubMed

LinkOut - more resources