Characterization of an IncL/M plasmid carrying blaOXA-48 in a Klebsiella pneumoniae strain from Italy
- PMID: 28994448
Characterization of an IncL/M plasmid carrying blaOXA-48 in a Klebsiella pneumoniae strain from Italy
Abstract
Here we report the complete nucleotide sequence of a 49.257-bp IncL/M conjugative plasmid (pRAY) carrying the blaOXA-48 gene collected from a Klebsiella pneumoniae clinical strain isolated in Italy. The genetic environment of pRAY plasmid revealed that the blaOXA-48 gene was located within a Tn1999.2 transposon. The pRAY plasmid differed from blaOXA-48-harboring IncL/M plasmids by genetic context and size. Comparative analysis demonstrated that pRAY plasmid lacked a region of ~15 kb carrying genes encoding proteins involved in pilus assembly and plasmid conjugative apparatus.
Keywords: Klebsiella pneumoniae; OXA-48; Plasmid.
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