doi: 10.1016/0014-2999(88)90052-0.
Effects of somatostatin on self-stimulation behaviour in rats pretreated with a receptor blocker
Affiliations
- PMID: 2899512
- DOI: 10.1016/0014-2999(88)90052-0
Item in Clipboard
Effects of somatostatin on self-stimulation behaviour in rats pretreated with a receptor blocker
Eur J Pharmacol.
.
Abstract
The effects of somatostatin on lateral hypothalamic self-stimulation were investigated in rats pretreated with haloperidol, bicuculline, phenoxybenzamine or propranolol. Somatostatin decreased the rate of self-stimulation. Halperidol, bicuculline and phenoxybenzamine potentiated the somatostatin-induced depression of self-stimulation behaviour. Propranolol had no effect. It is suggested that dopaminergic, GABAergic and noradrenergic systems are involved in the somatostatin-induced depression of self-stimulation.
Similar articles
-
The effect of linear somatostatin on the active avoidance behaviour and open-field activity on haloperidol, phenoxybenzamine and atropine pretreated rats.Acta Physiol Hung. 1983;62(3-4):205-11. Acta Physiol Hung. 1983. PMID: 6141699
-
The effect of somatostatin on self-stimulation behavior in atropine- and methysergide-pretreated rats.Eur J Pharmacol. 1983 Jul 15;91(1):89-93. doi: 10.1016/0014-2999(83)90366-7. Eur J Pharmacol. 1983. PMID: 6137393
-
Phenoxybenzamine antagonizes somatostatin-induced antiamnesia in rats.Eur J Pharmacol. 1984 Apr 6;99(4):325-8. doi: 10.1016/0014-2999(84)90139-0. Eur J Pharmacol. 1984. PMID: 6145603
-
Comparative studies with linear and cyclic somatostatin on the self-stimulation of rats.Acta Physiol Acad Sci Hung. 1982;60(3):165-8. Acta Physiol Acad Sci Hung. 1982. PMID: 6136151
-
Catecholaminergic influences on induced hippocampal paroxysmal activity in rats.Acta Physiol Pharmacol Latinoam. 1986;36(3):233-49. Acta Physiol Pharmacol Latinoam. 1986. PMID: 3577804
Cited by
-
Somatostatin-28 modulates prepulse inhibition of the acoustic startle response, reward processes and spontaneous locomotor activity in rats.Neuropeptides. 2010 Oct;44(5):421-9. doi: 10.1016/j.npep.2010.04.008. Neuropeptides. 2010. PMID: 20537385 Free PMC article.
-
Neurotransmitter regulation of somatostatin secretion by fetal rat cerebral cortical cells in culture.J Endocrinol Invest. 1993 Oct;16(9):661-8. doi: 10.1007/BF03348905. J Endocrinol Invest. 1993. PMID: 7904279
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
